Isa Bey Mosque is one of the Ottoman-era mosques located in the city of Izmir, Turkey. The mosque was built in 1375 by Aydinoglu Isa Bey. Located in the Selcuk district of Izmir, the mosque is considered beautiful example of Turkish-Islamic architecture.

The architectural style of the mosque combines Seljuk and Byzantine elements. The Byzantine reliefs on the main entrance and the Seljuk decorations inside the mosque reflect the influence of different cultures. The mosque's domes were built in the classical style of the Ottoman era.

The interior of Isa Bey Mosque is quite spacious and has a large courtyard. The mosque has one minaret located to the north. Various patterns on the ceilings are considered a beautiful example of art from the period. Additionally, the mosque's mihrab is decorated with Ottoman-era embroidery.