Ephesus is an ancient Greek and Roman city located on the west coast of modern-day Turkey, near the town of Selcuk in Izmir province. 

In ancient times, Ephesus was a major city in Asia Minor, and it was situated near to other important cities and settlements. For example, the city of Smyrna (present-day Izmir) was located approximately 70 kilometers (approximately 44 miles) north of Ephesus, and the city of Pergamum was located approximately 130 kilometers (approximately 80 miles) to the north.

Kusadasi: Kusadasi is a popular seaside resort town located approximately 18 kilometers (approximately 12 miles) south of the archaeological site of Ephesus. The journey from Ephesus to Kusadasi takes approximately 20-25 minutes by car.

Istanbul: Istanbul is located on the opposite side of the country from Ephesus, in the northwestern region of Turkey. The distance between Istanbul and Ephesus is approximately 675 kilometers (approximately 420 miles). The most common way to travel between the two cities is by plane, with a flight time of approximately 1 hour and 10 minutes. Alternatively, it is possible to take an overnight bus or train, which can take between 9-12 hours depending on the mode of transportation.

Cappadocia: Cappadocia is a region in central Turkey known for its unique landscape, rock formations, and underground cities. It is located approximately 750 kilometers (approximately 466 miles) northeast of Ephesus. The most common way to travel between the two destinations is by plane, with a flight time of approximately 1 hour and 15 minutes. Alternatively, it is possible to take an overnight bus or drive, which can take between 9-10 hours depending on traffic and road conditions.

Bodrum: The distance between Bodrum and Ephesus is approximately 145 kilometers (approximately 90 miles). If you're traveling by car, it takes around 2 hours and 15 minutes.